AN UNEXPLAINED TSUNAMI: WAS THERE MEGATHRUST SLIP DURING THE 2020 MW7.6 SAND POINT, ALASKA, EARTHQUAKE?


Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

Secreted Wnt proteins regulate development and adult tissue homeostasis by binding and activating cell-surface Frizzled receptors and co-receptors including LRP5/6.The hydrophobicity of Wnt proteins has complicated their purification and limited their use in basic research and as therapeutics.We describe modular tetravalent antibodies that can VERA

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